Trey Parker

Eric Cartman / Stan Marsh (voice)

Matt Stone

Kyle Broflovski / Kenny McCormick (voice)

Jennifer Howell

Bebe Stevens (voice)

Mona Marshall

Sheila Broflovski (voice)

April Stewart

Nelly (voice), Sharon Marsh (voice), News Reporter/Additional Voices (voice), Liane Cartman / Sharon Marsh / Tammy Thompson (voice), Sharon Marsh / Liane Cartman (voice), Sharon Marsh / Shelley Marsh (voice), Wendy Testaburger / Liane Cartman / Dora Márquez (voice), Shanon Marsh (voice)

Isaac Hayes

Chef (voice)

Eliza Schneider

Liane Cartman (voice), Principal Victoria/Elderly Woman/Swearing Woman #1/Swearing Woman #2/Cocktail Waitress( voice)

Mary Kay Bergman

Liane Cartman / Wendy Testaburger / Sharon Marsh / Sheila Broflovski (voice)

Adrien Beard

Token Black (voice), Tolkien Black (voice)

Kyle McCulloch

Excalibur Hotel Employee (voice)

Milan Agnone

Ike Broflovski (voice)

Sebastian Yu

Ike Broflovski (voice)

Jessie Jo Thomas

Jonathan Kimmel

Jimmy Kimmel (voice)

John Hansen

John Travolta (voice), Mr. Slave / Trucker (voice)

Toddy Walters

Mall Hankey's Helper (voice)

Eric Stough

Kenny McCormick (voice)

Kimberly Brooks

Dora (voice), ChatGPT / Anna Paulina Luna (voice), Linda Black (voice), Theresa (voice), Laura Tucker / Kipling (voice), Nicole (voice) (As Laylo Incognegro)

Jessica Makinson

Heidi Turner (voice)

Dian Bachar

Fake Mr. Hankey (voice)

Bill Hader

Newsman, Plex the robot, Farmer # 2, Alec Baldwin

Betty Boogie Parker

Priest Call Whistler (voice), Betsy (voice), Ike Broflovski (voice)

Frank Welker

Elton John

Sir Elton John (voice)

Jay Leno

Jay Leno (voice)

Franchesca Clifford

Ike Broflovski (voice), Ike Broflovski (archive sound) (voice)

Felix Kjellberg

PewDiePie

Brock Baker

Winnie the Pooh (voice)

Bruce Howell

(voice), Uncle Murray (voice)

Brad Paisley

"We Are South America" Singer, Self

Ronnie James Dio

Peter Serafinowicz

Darth Chef (voice)

Erica Rivinoja

Meat Loaf

Meat Loaf (voice)

Malcolm McDowell

A British Person (voice)

Norman Lear

Tommy Chong

Chief Running Pinto (voice)

Gian Ganziano

Thom Yorke

Thom Yorke

Robert Smith

Robert Smith

Marc Shaiman

Jennifer Aniston

Mrs. Stevens (Choir Teacher) (voice)

Natasha Henstridge

Ms. Ellen (voice)

Henry Winkler

The Scary Monster (voice)

George Clooney

Sparky (voice)

Jonathan Katz

Dr. Katz (voice)

Yao Ming

Richard Belzer

Loogie (voice)

Michael Buffer

Karri Turner

Kathie Lee Gifford (voice)

Cheech Marin

Carlos Ramirez (voice)

Daniel O'Donnell

Diedrich Bader

Bat Dad (voice) (uncredited)

Brent Musburger

Brent Musburger (voice)

DMX

DMX (voice)

Joe Strummer

Joe Strummer (voice)

Ol' Dirty Bastard

Ol' Dirty Bastard (voice)

Ozzy Osbourne

Ozzy Osbourne (voice)

Rick James

Rick James (voice)

Eric Bauza

Pubescent Ike

Sullivan Braun

Real-Life Kyle

Rowan Smyth

Real-life Butters

Dave Tennant

Jonny Greenwood

Jonny Greenwood

Ed O'Brien

Ed O'Brien

Colin Greenwood

Colin Greenwood

Philip Selway

Philip Selway

Brian "Head" Welch

Matthew Thorson Benavides

Real-life Stan

Max Kalvan

Real-life Kenny

Kellen Michael

Real-life Eric

Jesse Brant Howell

Ike Broflovski (voice)

Nico Agnone

Young Stan / Young Kyle (voice)

Les Claypool

Les Claypool (voice)

Tim Armstrong

Rancid (voice)

Scott Kirkland

The Crystal Method (voice)

Ken Jordan

The Crystal Method (voice)

Dean Ween

Ween (voice) (as Dean Ween)

Gene Ween

Ween (voice) (as Gene Ween)

Genevive Colvin

Vocals (voice)

Charles Manson

Charles Manson (archive footage)

Stanley G. Sawicki

Larry (voice)

Pam Brady

Woman

Sarah Kane

Grandma

George Brandon

Uncle Corey

Saki Miata

Woman in Live Action Commercial

Delilah Kujala

Amazon Alexa (voice)

Vernon Chatman

Towlie (voice)

Elisa Gabrielli

Laura Tucker (voice)

Elon Musk

Elon Musk (voice)

Jessica Jang

Wing Han Tsang (voice)

Josh Gad

Marcus

Mike Judge

Kenny McCormick (voice)