Billy West

Fry / Professor Farnsworth / Zoidberg / Zapp Brannigan (voice)

Katey Sagal

Leela (voice)

John DiMaggio

Bender (voice)

Tress MacNeille

Mom (voice)

Maurice LaMarche

Morbo / Kif Kroker (voice)

Lauren Tom

Amy Wong (voice)

Phil LaMarr

Hermes Conrad (voice)

David Herman

Scruffy (voice)

Frank Welker

Nibbler (voice), Tardigrades (voice), Nibbler / Supercat (voice), Nibbler / Pygmy Hyena Moles (voice), Mountain Lion (voice), Raccoon / Plants (voice)

Dawnn Lewis

Brainormous (voice), LaBarbara Conrad (voice), LaBarbara Conrad / Influencer (voice), Coco Charm / Ensign Zinc (voice), Jackie Anderson (voice), Nurse (voice), LaBarbara Conrad / Hermes' Mother (voice)

Kath Soucie

Nina / Albert / Various Orphans (voice), Cubert Farnsworth / Casting Director / Emotitron Jr. / Children at Party (voice), Albert / Nina (voice), Nina (voice), Albert / Nina / Orphans (voice), Cubert Farnsworth / The Real World Announcer (voice), Michelle / Rude Boy / Head Museum Feeder (voice), Cubert Farnsworth (voice), Cubert Farnsworth / Rude Boy (voice), Punk Kid / Butch's Girlfriend / Various Children (voice), Cubert Farnsworth / Little Kids (voice), Princess Num Num (voice)

Tom Kenny

Abner Doubledeal (voice), The Masked Unit / Abner Doubledeal (voice), Abner Doubledeal / Yancy Fry Jr. / Gamester Alien (voice)

Kevin Michael Richardson

URL (voice), Barbados Slim (voice), URL / Barbados Slim / Curly Joe (voice)

Dan Castellaneta

Robot Devil (voice), The Robot Devil (voice)

George Takei

George Takei's Head (voice)

Feodor Chin

Leo Wong (voice), Scoop Chang (voice)

Dee Bradley Baker

Gamester Alien #2 / Donkey Monster (voice), Yogurt Creature (voice), Rusty the Donkey (voice), Georg Cantor (voice), Snipe (voice)

Cara Delevingne

Makeup Robot (voice), Cara Delevingne (voice), Owl (voice), TV Special Screams (voice)

Al Gore

Al Gore (voice)

Coolio

Kwanzaabot (voice)

Phil Hendrie

Free Waterfall Junior (voice), Groovestick Waterfall / Bliss Waterfall / Waterfall Offspring (voice)

Bill Nye

Bill Nye the Science Head (voice)

Leonard Nimoy

Leonard Nimoy's Head (Voice)

Nichelle Nichols

Nichelle Nichols' Head (voice)

David X. Cohen

Computer (voice)

Stephen Hawking

Stephen Hawking (voice)

Pamela Anderson

Dixie (voice), Pamela Anderson's head (voice)

Sarah Silverman

Michelle (voice)

Lucy Liu

Lucy Liu's Head (voice)

Kyle MacLachlan

Kyle MacLachlan's Head (voice), Dung Beetle (voice)

Nicole St. John

Sally (voice)

Renée Victor

Abuelatron (voice), Pottery Bot / Abuelatron (voice)

Walter Koenig

Walter Koenig (voice)

Ron Popeil

Ron Popeil's head (voice)

Claudia Schiffer

Claudia Schiffer's head (voice)

Hank Azaria

Harold Zoid (voice)

Dick Clark

Dick Clark's Head (voice)

Rich Little

Rich Little's Head as Howard Cosell (voice)

Donovan

Donovan (voice)

Bob Barker

Bob Barker (voice)

Jan Hooks

Anglelyne (voice)

Bea Arthur

Femputer (voice)

Conan O'Brien

Self (voice)

Adam Horovitz

Ad-Rock / MCA (voice)

Nora Dunn

Morgan Proctor (voice)

Suzie Plakson

Amazonian (voice)

John Goodman

Robot Santa Claus (voice)

Sigourney Weaver

Planet Express Ship (voice)

Nancy Cartwright

Bart Simpson Doll (voice)

Parker Posey

Umbriel (voice)

Michael Diamond

Mike D's head (voice)

William Shatner

William Shatner (voice)

Jonathan Frakes

Jonathan Frakes (voice)

Gary Gygax

Gary Gygax (voice)

Todd Susman

Announcer (voice)

Pauly Shore

Pauly Shore (voice)

Bob Uecker

Bob Uecker (voice)

Hank Aaron

Hank Aaron (voice)

Roseanne Barr

Roseanne Barr (voice)

Emilia Clarke

Marianne (voice)

Craig Ferguson

Susan Boil (voice)

Chris Elliott

V-Giny (voice)

Katee Sackhoff

Grrrl (voice)

Matt Groening

Matt Groening (voice)

Sergio Aragonés

Sergio Aragonés (voice)

Mark Mothersbaugh

Mark Mothersbaugh (voice)

Patton Oswalt

Unattractive Giant Monster (voice)

Buzz Aldrin

Buzz Aldrin (voice)

Wanda Sykes

Bev (voice)

Jill Talley

Trainer (voice)

Estelle Harris

Velma Farnsworth (voice)

Patrick Stewart

Huntmaster (voice)

Larry Bird

Larry Bird (voice)

Robert Wagner

Robert Wagner's Head (voice)

Adam West

Adam West (voice)

Burt Ward

Burt Ward (voice)

Seth MacFarlane

Seymour (voice)

Tara Strong

Tanya (voice)

Karen Maruyama

Amazonian (voice)

Brad Norman

PC (voice)

Patric M. Verrone

Patric M. Verrone (voice)

Ego Nwodim

Dung Beetle Shaman (voice)

Mark Hamill

Chanukah Zombie (voice)

Kathy Griffin

Captain Cranky (voice)

Beck

Beck's head (voice)

Russ Leatherman

Mr. Moviefone (voice)

Bob Odenkirk

Chaz (voice)

Dan Vebber

Norwegian seed guard (voice)

Danny Trejo

Doblando Rodriguez (voice)

Carlos Alazraqui

Referee Bot (voice)

Gabriel Romero

Ancient Emperor (voice)

Diana Elizabeth Torres

Sobrina Rodriguez / Ancient Empress (voice)

Ana Ortiz

Marquita (voice)

Tim Gunn

Tim Gunn's Head (voice)

Aleque Reid

Umbriel (voice)

Zuri Washington

Jamaican Woman (voice)

LeVar Burton

Unlicensed Hologram of LeVar Burton (voice)

Neil deGrasse Tyson

Neil deGrasse Tyson (voice)

Guillermo del Toro

Guillermo del Toro's Head (voice)

Victor Wembanyama

Wembanyana (voice)

Kenny G

Kenny G's Head (voice)

Ravi Patel

Ipgee (voice)

Danica McKellar

Dancia McKellar's Head (voice)

Maria Bamford

Jambone (voice)

Caitlin Gallogly

Marianne (voice)

Abbi Jacobson

Bean (voice)

Eric Andre

Luci / Sir Pendergast (voice)

Nat Faxon

Elfo (voice)

Sharon Horgan

Queen Dagmar (voice)

Lucy Montgomery

Bunty (voice)

Rich Fulcher

Sir Turbish (voice)